TOP PAGE　＞　研究内容（４）　＞　デンドリマーに関する原著論文と総説

デンドリマーに関する原著論文と総説

X. Li, Y. Haba, K. Ochi, E. Yuba, A. Harada, K. Kono, " PAMAM dendrimers with oxyethylene unit-enriched surface as biocompatible temperature-sensitive dendrimers", Bioconjugate Chem., 24, 282-290 (2013). DOI:10.1021/bc300190v
K. Kono, "Dendrimer-based bionanomaterials produced by surface modification, assembly, and hybrid formation", Polymer Journal, 44, 531-540 (2012). (総説） DOI:10.1038/pj.2012.39
河野健司, 「機能性デンドリマーとＤＤＳ」, 先端バイオマテリアル, pp. 347-357 (2012) エヌ・ティー・エス．
C. Kojima, B. Turkbey, M. Ogawa, M. Bernardo, C. A. S. Regino, L. H. Bryant, Jr., P. L. Choyke, K. Kono, H. Kobayashi, "Dendrimer-based MRI contrast agents: the effects of PEGylation on relaxivity and pharmacokinetics", Nanomedicine-Nanotechnology Biology and Medicine, 7, 1001-1008 (2011). DOI:10.1016/j.nano.2011.03.007
K. Kono, E. Murakami, Y. Hiranaka, E. Yuba, C. Kojima, A. Harada, K.Sakurai, "Thermosensitive molecular assemblies from PAMAM dendron-basedlipids", Angew. Chem. Int. Ed. 50, 6332-6336 (2011). DOI:10.1002/anie.201101007
C. Kojima, Y. Umeda, A. Harada, K. Kono, "Preparation of near-infrared light absorbing gold nanoparticles using polyethylene glycol-attached dendrimers", Colloids Surf. B:Biointerfaces, 81, 648-651 (2010). DOI:10.1016/j.colsurfb.2010.07.060
Y. Umeda, C. Kojima, A. Harada, H. Horinaka, K. Kono, "PEG-attached PAMAM dendrimers encapsulating gold nanoparticles: growing gold nanoparticles in the dendrimers for improvement of their photothermal properties", Bioconjugate Chem., 21, 1559-1564 (2010). DOI:10.1021/bc1001399
C. Kojima, Y. Umeda, M. Ogawa, A. Harada, Y. Magata, K. Kono, "X-ray computed tomography contrast agents prepared by seeded growth of gold nanoparticle in PEGylated dendrimer", Nanotechnology, 21, 245104 (2010).
T. Suehiro, C. Kojima, S. Tsumura, A. Harada, K. Kono, "Higher order structure of short collagen model peptides attached to dendrimers and linear polymers", Biopolymers, 93, 640-648 (2010).
C. Kojima, C. Regino, Y. Umeda, H. Kobayashi, K. Kono, "Influence of dendrimer generation and polyethylene glycol length on the biodistribution of pegylated dendrimers", Int. J. Pharm., 383, 293-296 (2010). DOI:10.1016/j.ijpharm.2009.09.015
C. Kojima, S. Tsumura, A. Harada, K. Kono, "A collagen-mimic dendrimer capable of controlled release", J. Am. Chem. Soc., 131, 6052-6053 (2009).
C. Kojima, Y. Toi, A. Harada, K. Kono, "Aqueous solubilization of fullerenes using poly(amidoamine) dendrimers bearing cyclodextrin and poly(ethylene glycol)", Bioconjugate Chem., 19, 2280-2284 (2008).
K. Kono, T. Fukui, T. Takagishi, S. Sakurai, C. Kojima, "Preparation of poly(ethylene glycol)-modified poly(amidoamine) dendrimers with a shell of hydrophobic amino acid residues and their function as a nanocontainer", Polymer, 49, 2832-2838 (2008).
K. Kono, C. Kojima, N. Hayashi, E. Nishisaka, K. Kiura, S. Watarai, A. Harada, "Preparation and cytotoxic activity of poly(ethylene glycol)-modified poly(amidoamine) dendrimers bearing adriamycin", Biomaterials, 29, 1664-1675 (2008).
K. Kono, T. Miyoshi, Y. Haba, E. Murakami, C. Kojima, A. Harada, "Temperature sensitivity control of alkylamide-terminated poly(amidoamine) dendrimers induced by guest molecule binding", J. Am. Chem. Soc., 129, 7222-7223 (2007).
Y. Haba, C. Kojima, A. Harada, T. Ura, H. Horinaka, K. Kono, "Preparation of poly(ethylene glycol)-modified poly(amidoamine) dendrimers encapsulating gold nanoparticles and their heat-generating ability", Langmuir, 23, 5243-5246 (2007).
C. Kojima, Y. Toi, A. Harada, K. Kono, "Preparation of polyethylene glycol-attached dendrimers encapsulating photosensitizers for application to photodynamic therapy", Bioconjugate Chem., 18, 663-670 (2007).
Y. Haba, C. Kojima, A. Harada, K. Kono, "Comparison of thermosensitive properties between poly(amidoamine) dendrimers having peripheral N-isopropylamide groups and linear polymers with the same groups", Angew. Chem. Int. Ed., 46, 234-237 (2007).
Y. Haba, C. Kojima, A. Harada, K. Kono, "Control of temperature-sensitive properties of poly(amidoamine) dendrimers using peripheral modification with various alkylamide groups", Macromolecules, 39, 7451-7453 (2006).
Y. Tono, C. Kojima, Y. Haba, T. Takahashi, A. Harada, S. Yagi, K. Kono, "Thermosensitive properties of poly(amidoamine) dendrimers with peripheral phenylalanine residues", Langmuir, 22, 4920-4922 (2006).
河野健司，児島千恵，「バイオメディカル機能と応用技術」，デンドリティック高分子，青井啓悟，柿本雅明　監修, pp. 319-381 (2005), エヌ・ティー・エス．
Y. Haba, A. Harada, T. Takagishi, K. Kono, "Synthesis of biocompatible dendrimers with a peripheral network formed by linking of polymerizable groups", Polymer, 46, 1813-1820 (2005).
Y. Haba, A. Harada, T. Takagishi, K. Kono, "Rendering poly(amidoamine) or poly(propylenimine) dendrimers temperature sensitive", J. Am. Chem. Soc., 126, 12760-12761 (2004).
C. Kojima, Y. Haba, T. Fukui, K. Kono, T. Takagishi, "Design of biocompatible dendrimers with environment-sensitivity", Macromolecules, 36, 2183-2186 (2003).
河野健司，「デンドリマーのＤＤＳへの応用」，Drug Delivery System, 17, 462-470 (2002).
K. Kono, C. Kojima, T. Fukui, T. Takagishi, "Design of polyamidoamine dendrimers with poly(ethylene glycol) chains as drug carriers", Polym. Mat. Sci. Eng., 84, 216-217 (2001).
C. Kojima, K. Kono, K. Maruyama, T. Takagishi, "Synthesis of polyamidoamine dendrimers having polyethylene glycol grafts and their ability to encapsulate anticancer drugs", Bioconjugate Chem., 11, 910-917 (2000).
M. Liu, K. Kono, J. M. J. Frechet, "Water-soluble dendritic unimolecular micelles: their potential as drug delivery agents", J. Control. Release, 65, 121-131 (2000).
K. Kono, M. Liu, J. M. J. Frechet, "Design of dendritic macromolecules containing folate or methotrexate residues", Bioconjugate Chem., 10, 1115-1121 (1999).
M. Liu, K. Kono, J. M. J. Frechet, "Water-soluble dendrimer-poly(ethylene glycol) starlike conjugates as potential drug carriers", J. Polym. Sci. Part A: Polym. Chem., 37, 3492-3503 (1999).
M. Liu, K. Kono, J. M. J. Frechet, "Water-soluble dendrimers as potential drug carriers", Polym. Mat. Sci. Eng., 79, 269-270 (1998).

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