E. Yuba, T. Korenaga, A. Harada, “Hydrophilic hyperbranched polymer-coated siRNA/polyamidoamine dendron-bearing lipid complexes preparation for high colloidal stability and efficient RNAi”, Bioconjugate Chemistry, , in press. DOI:
E. Yuba, K. Kono, "Nasal delivery of biopharmaceuticals", In "Mucosal Delivery of Biopharmaceuticals", pp.197-220, Springer Science, New York (2014). DOI:10.1007/978-1-4614-9524-6_8.
K. Kono, "Polymer-based nanomaterials for drug delivery", in Environmentally Harmonious Chemistry for the 21st Century, M. Anpo, K. Mizuno (Eds), pp. 149-162, Nova Science Publishers, NY (2010).
K. Kono, T. Fukui, T. Takagishi, S. Sakurai, C. Kojima, "Preparation of poly(ethylene glycol)-modified poly(amidoamine) dendrimers with a shell of hydrophobic amino acid residues and their function as a nanocontainer", Polymer, 49, 2832-2838 (2008).
N. Sakaguchi, C. Kojima, A. Harada, K. Kono, "Preparation of pH-sensitive poly(glycidol) derivatives with varying hydrophobicities: their ability to sensitize stable liposomes to pH", Bioconjugate Chem., 19, 1040-1048 (2008).
A. Kawamura, C. Kojima, M. Iijima, A. Harada, K. Kono, "Polyion complex micelles formed from glucose oxidase and comb-type polyelectrolyte with poly(ethylene glycol) grafts", J. Polym. Sci. Part A: Polym. Chem., 46, 3842-3852 (2008).
K. Kono, C. Kojima, N. Hayashi, E. Nishisaka, K. Kiura, S. Watarai, A. Harada, "Preparation and cytotoxic activity of poly(ethylene glycol)-modified poly(amidoamine) dendrimers bearing adriamycin", Biomaterials, 29, 1664-1675 (2008).
N. Sakaguchi, C. Kojima, A. Harada, K. Koiwai, K. Shimizu, N. Emi, K. Kono, "Generation of highly potent nonviral gene vectors by complexation of lipoplexes and transferrin-bearing fusogenic polymer-modified liposomes in aqueous glucose solution", Biomaterials, 29, 1262-1272 (2008).
H. Horinaka, T. Matsunaka, N. Nakamura, T. Mukaiyama, S. Kawakami, K. Wada, Y. Hirano, C. Kojima, K. Kono, "Gold nanoparticle distribution monitor for drug delivery system based on optically assisted ultrasonic velocity-change imaging", Electronics Letters, 43, 1254-1255 (2007).
A. Harada, K. Johnin, A. Kawamura,K. Kono, "Preparation of temperature-responsive polymer gels physically immobilizing core-shell type bioconjugates", J. Polym. Sci. Part A: Polym. Chem., 45, 5942-5948 (2007).
A. Kawamura, A. Harada, K. Kono, K. Kataoka, "Self-assembled nano-bioreactor from block ionomers with elevated and stabilized enzymatic function", Bioconjugate Chem., 18, 1555-1559 (2007).
K. Kono, T. Miyoshi, Y. Haba, E. Murakami, C. Kojima, A. Harada, "Temperature sensitivity control of alkylamide-terminated poly(amidoamine) dendrimers induced by guest molecule binding", J. Am. Chem. Soc., 129, 7222-7223 (2007).
T. Takahashi, J. Hirose, C. Kojima, A. Harada, K. Kono, "Synthesis of poly(amidoamine) dendron-bearing lipids with poly(ethylene glycol) grafts and their use for stabilization of nonviral gene vectors", Bioconjugate Chem., 18, 1163-1169 (2007).
T. Takahashi, C. Kojima, A. Harada, K. Kono, "Alkyl chain moieties of polyamidoamine dendron-bearing lipids influence their function as a nonviral gene vector", Bioconjugate Chem., 18, 1349-1354 (2007).
Y. Haba, C. Kojima, A. Harada, T. Ura, H. Horinaka, K. Kono, "Preparation of poly(ethylene glycol)-modified poly(amidoamine) dendrimers encapsulating gold nanoparticles and their heat-generating ability", Langmuir, 23, 5243-5246 (2007).
C. Kojima, Y. Toi, A. Harada, K. Kono, "Preparation of polyethylene glycol-attached dendrimers encapsulating photosensitizers for application to photodynamic therapy", Bioconjugate Chem., 18, 663-670 (2007).
A. Harada, Y. Yoshioka, A. Kawamura, C. Kojima, K. Kono, "Effect of polycarboxylate block on the amidase activity of trypsin through complexation with peg-polycarboxylate block ionomers", Macromol. Biosci., 7, 339-343 (2007).
S. Kakinoki, M. Kitamura, M. Yuge, M. Furuta, M. Oka, Y. Hirano, K. Kono, I. Kaetsu, "Solution property and irradiation effect of random copolypeptides composed of Ala and Pro residues", Polym. Bull., 58, 393-400 (2007).
Y. Haba, C. Kojima, A. Harada, K. Kono, "Comparison of thermosensitive properties between poly(amidoamine) dendrimers having peripheral N-isopropylamide groups and linear polymers with the same groups", Angew. Chem. Int. Ed., 46, 234-237 (2007).
A. Harada, K. Kataoka, "Supramolecular assemblies of block copolymers in aqueous media as nanocontainers relevant to biological applications", Prog. Polym. Sci., 31, 949-982 (2006).
A. Harada, K. Kataoka, "Stimuli responsive polyion complex assemblies", MML Series 7, Smart Nano and Microparticles, K. Kono, R. Arshady (eds.), pp. 210-229, Kentus Books, London (2006).
K. Kono, "Stimuli responsive polymer-liposomes: formulation and in vitro evaluation", MML Series 7, Smart Nano and Microparticles, K. Kono, R. Arshady (eds.), pp. 91-123, Kentus Books, London (2006).
Y. Haba, C. Kojima, A. Harada, K. Kono, "Control of temperature-sensitive properties of poly(amidoamine) dendrimers using peripheral modification with various alkylamide groups",
Macromolecules, 39, 7451-7453 (2006).
N. Sakaguchi, C. Kojima, A. Harada, K. Koiwai, K. Shimizu, N. Emi, K. Kono, "Enhancement of transfection activity of lipoplexes by complexation with transferrin-bearing fusogenic polymer-modified liposomes", Int. J. Pharm., 325, 186-190 (2006).
Y. Tono, C. Kojima, Y. Haba, T. Takahashi, A. Harada, S. Yagi, K. Kono, "Thermosensitive properties of poly (amidoamine) dendrimers with peripheral phenylalanine residues", Langmuir,
22, 4920-4922 (2006).
A. Harada, M. Kawamura, T. Matsuo, T. Takahashi, K. Kono, "Synthesis and characterization of head-tail type polycation block copolymer as non-viral gene vector", Bioconjugate Chem., 17, 3-5 (2006).
K. Kono, T. Murakami, T. Yoshida, Y. Haba, S. Kanaoka, T. Takagishi, S. Aoshima, "Temperature-sensitization of liposomes by use of thermosensitive block copolymers synthesized by living cationic polymerization", Bioconjugate Chem., 16, 1367-1374 (2005).
T. Takahashi, A. Harada, N. Emi, K. Kono, "Preparation of efficient gene carriers using a polyamidoamine dendron-bearing lipid: improvement of serum resistance", Bioconjugate Chem., 16, 1160-1165 (2005).
A. Kawamura, Y. Yoshioka, A. Harada, K. Kono, "Acceleration of enzymatic reaction of trypsin through the formation of water-soluble complexes with poly(ethylene glycol)-block-poly(α, β-aspartic acid)", Biomacromolecules, 6, 627-631 (2005).
K. Kono, H. Akiyama, T. Takahashi, T. Takagishi, A. Harada, "Transfection activity of polyamidoamine dendrimers having hydrophobic amino acid residues in the periphery", Bioconjugate Chem., 16, 208-214 (2005).
Y. Haba, A. Harada, T. Takagishi, K. Kono, "Synthesis of biocompatible dendrimers with a peripheral network formed by linking of polymerizable groups", Polymer, 46, 1813-1820 (2005).